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Title: Genetics in the study of mosquito susceptibility to Plasmodium. Author: Collins FH, Saunders RD, Kafatos FC, Roth C, Ke Z, Wang X, Dymbrowski K, Ton L, Hogan J. Journal: Parassitologia; 1999 Sep; 41(1-3):163-8. PubMed ID: 10697850. Abstract: Within the past several years, a number of powerful genetic and genomic tools have been developed for use in research on the African malaria vector Anopheles gambiae. While these tools have been developed with a broad range of potential applications in mind, they have been particularly useful in advancing the effort to clone a set of An. gambiae genes that enable a refractory strain of this mosquito to encapsulate and kill a wide variety of different malaria parasites to which this mosquito is normally fully susceptible. This paper describes the latest progress in this map-based cloning research, which involves the collaborative contributions of a number of different laboratories in Europe and the United States.[Abstract] [Full Text] [Related] [New Search]