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  • Title: [Changes in the virulence factor expression level in Listeria monocytogenes under various environmental conditions].
    Author: Ermolaeva SA, Belyĭ IuF, Tartakovskiĭ IS.
    Journal: Mol Gen Mikrobiol Virusol; 2000; (1):17-9. PubMed ID: 10702985.
    Abstract:
    Effects of chelators Chelex-100 and activated charcoal on the production of proteins responsible for virulence of Listeria monocytogenes, facultative intracellular parasite were studied. Bivalent cation chelator Chelex-100 stimulates the production of only thiol-dependent hemolysin listeriolysin O. The presence of activated charcoal, a nonspecific chelator, in culture medium stimulated the expression of listeriolysin O and other main virulence factors by increasing the level of their transcription.
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