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  • Title: Tuberculosis and Pelger-Huët anomaly. Case report.
    Author: Cicchitto G, Parravicini M, De Lorenzo S, Di Pisa G, Malacrida A.
    Journal: Panminerva Med; 1999 Dec; 41(4):367-9. PubMed ID: 10705722.
    Abstract:
    We describe a patient with pulmonary tuberculosis and a rare disturbance of leukocyte segmentation, known as "Pelger-Huët anomaly", which can be observed in various diseases such as malignancies and/or infections. The importance of this association is equivocal: some authors have related to the association the particular severity of tuberculosis or the death they observed; in the case reported we noted no evidence of such a relation, notwithstanding the presence of the homozygous form of the Pelger-Huët anomaly. We suggest therefore that, when Pelger-Huët anomaly is found, an underlying disease should be searched for; the course of this illness, however, might not be affected.
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