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  • Title: Antibody against a novel, myriocin (ISP-I)-based immunosuppressant, FTY720.
    Author: Fujita T, Matsumoto N, Uchida S, Kohno T, Shimizu T, Hirose R, Yanada K, Kurio W, Watabe K.
    Journal: Bioorg Med Chem Lett; 2000 Feb 21; 10(4):337-9. PubMed ID: 10714494.
    Abstract:
    An antibody was prepared by immunizing rabbits with an ovalbumin conjugate of 2-amino-2-(2-(4-(4-mercaptobutyl)phenyl)ethyl)propane-1,3-diol HCl (AMPD-4), which contains the essential structure of the novel immunosuppressant FTY720. As the antibody reacted to not only AMPD-4, but also FTY720, it should be useful for immunoassay of FTY720 in body fluids, tissues and cells.
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