These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in immunocompromised patients.
    Author: Armstrong W, Meshnick S, Kazanjian P.
    Journal: Microbes Infect; 2000 Jan; 2(1):61-7. PubMed ID: 10717542.
    Abstract:
    Recent studies have shown that mutations in two amino acid positions of the Pneumocystis carinii dihydropteroate synthase gene are significantly more common in immunocompromised patients with P. carinii pneumonia who fail sulfa or sulfone prophylaxis. This paper reviews the studies that suggest that these mutations may be responsible for some failures of prophylaxis in P. carinii.
    [Abstract] [Full Text] [Related] [New Search]