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  • Title: Synthesis of 3-substituted phenacyl-5-[2-phenyl-4H-4-oxo-1-benzopyran-6- yl)methylenyl]-thiazolidine-2,4-diones and evaluation of their antimicrobial activity.
    Author: Ayhan-Kilcigil G, Altanlar N.
    Journal: Arzneimittelforschung; 2000 Feb; 50(2):154-7. PubMed ID: 10719619.
    Abstract:
    Synthesis and physico-chemical properties of two 3-substituted phenacyl-thiazolidine-2,4-diones (2c-d) and four 3-substituted phenacyl-5-[2-phenyl-4H-4-oxo-1-benzopyran-6-yl)methyl-enyl]-thiazolidin e- 2,4-diones (4a-d) are described. These products were synthesized by Knoevenagel reaction from flavone-6-carboxaldehyde (3) and 3-(substituted phenacyl)- thiazolidine-2,4-diones (2a-d). Antibacterial and antifungal activities were investigated for these compounds.
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