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  • Title: New cytotoxic agents, BE-54238A and B, produced by a streptomycete.
    Author: Tsukamoto M, Nakajima S, Murooka K, Hirayama M, Hirano K, Yoshida S, Kojiri K, Suda H.
    Journal: J Antibiot (Tokyo); 2000 Jan; 53(1):26-32. PubMed ID: 10724004.
    Abstract:
    New cytotoxic substances, designated BE-54238A and B, were isolated from the culture broth of Streptomyces sp. A54238. The active principles were extracted from the mycelium by methanol and purified by Diaion HP-20 and Sephadex LH-20 column chromatographies. BE-54238A and B exhibited cytotoxic activity against murine and human tumor cell lines.
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