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  • Title: [Extra-neoplastic epithelial changes in cancer of the vulva].
    Author: Ivanova R, Veselinova T, Marinov E, Gorchev G, Tsetkov Ch, Lalov S.
    Journal: Akush Ginekol (Sofiia); 1999; 38(4):35-7. PubMed ID: 10726352.
    Abstract:
    A retrospective morphological research is made on the material of 78 cases from vulva for a three years period of time. They are identified 35 cases with invasive carcinoma, 2 c. with noninvasive carcinoma, 19 c. with vulvar dystrophia and squamous intraepithelial neoplasia (VIN). The invasive carcinomas are divided: keratinizing squamous cell carcinoma--31 c.; nonkeratinizing squamous cell carcinoma--3 c; adenoid squamous cell carcinoma--1. In all operated patients are examined the changes in the tissues surrounding the tumor and in the underlying tissue. They are divided in: lichen sclerosus, squamous cell hyperplasia, mixed dystrophia and squamous intraepithelial neoplasia. The morphological variants of squamous carcinoma, the epithelial changes and the patient's age are paralleled.
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