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  • Title: HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles.
    Author: Pravenec M, Kren V, Krenová D, Bíla V, Zídek V, Simáková M, Musilová A, van Lith HA, van Zutphen LF.
    Journal: Folia Biol (Praha); 1999; 45(5):203-15. PubMed ID: 10730889.
    Abstract:
    The HXB/Ipcv and BXH/Cub sets of recombinant inbred (RI) strains were derived from the spontaneously hypertensive rats (SHR/OlaIpcv) and normotensive Brown Norway (BN-Lx/Cub) rats. The RI strains were produced as a model system for genetic and correlation analysis of spontaneous hypertension and other risk factors of cardiovascular disease such as insulin resistance and dyslipidemia. The RI strains were phenotyped in multiple hemodynamic and metabolic traits. In the current study, we describe strain distribution patterns of 632 genetic markers.
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