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  • Title: Brainstem encephalitis resulting from Epstein-Barr virus mimicking an infiltrating tumor in a child.
    Author: Angelini L, Bugiani M, Zibordi F, Cinque P, Bizzi A.
    Journal: Pediatr Neurol; 2000 Feb; 22(2):130-2. PubMed ID: 10738918.
    Abstract:
    A case of a child with subacute neurologic features and imaging findings consistent with a brainstem encephalitis that was discovered to be related to a primary central nervous system infection caused by Epstein-Barr virus is presented. A brainstem tumor was initially suspected, but a correct diagnosis was formulated on the basis of the favorable clinical course and the detection of positive Epstein-Barr virus serology. In contrast to a prompt recovery of neurologic signs the neuroimaging alterations persisted for a longer time. The present report emphasizes the possible role of Epstein-Barr virus in the pathogenesis of infectious neurologic disorders in childhood, underlining the unusual presentation of a brainstem encephalitis, and considers the discrepancy between the course of neurologic features and the evolution of imaging alterations.
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