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  • Title: [Hepatic MALT lymphoma disclosing a nodal extension].
    Author: Charton-Bain MC, Lelong B, Bouabdallah R, Dubus P, Merlio JP, Hassoun J, Xerri L.
    Journal: Ann Pathol; 2000 Mar; 20(2):137-41. PubMed ID: 10740010.
    Abstract:
    We report a case of a 50-year-old man with chronic viral hepatitis B presenting with a primary hepatic lymphoma of mucosa-associated lymphoid tissue, revealed clinically by a pedicular nodal mass. The liver biopsy showed an active chronic hepatitis and a dense portal lymphoid infiltrate with centrocyte-like cells inducing typical biliary lympho-epithelial lesions. The lymph-node biopsy revealed a marginal zone lymphoma pattern. A monoclonal rearrangement of the immunoglobulin heavy chain gene was detected in the lymph node by polymerase chain reaction. This case of primary hepatic mucosa-associated lymphoid tissue lymphoma confirms that the liver also contains mucosa-associated lymphoid tissue, in which low grade lymphoma can arise.
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