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  • Title: [Long-term results of small cell lung cancer treated by surgery combined with postoperative chemotherapy: a report of 65 patients].
    Author: Zhang X, Sun Y, Huang J.
    Journal: Zhonghua Zhong Liu Za Zhi; 1997 Mar; 19(2):137-9. PubMed ID: 10743080.
    Abstract:
    OBJECTIVE: To analyse the long term results of small cell lung cancer (SCLC) treated by surgery combined with postoperative chemotherapy. METHODS: From 1983 to 1994, 65 patients with SCLC were treated by surgery combined with postoperative chemotherapy, and 22 of them received prophylactic cranial irradiation. RESULTS: In 64 evaluable patients, the overall 1-, 3- and 5-year survival rates were 87.5%, 53.2% and 36.3%. Patients treated by radical operation plus chemotherapy gave 1-, 3- and 5-year survival rates of 92.5%, 58.5% and 43.8%. The prognostic surviving factors as analysed showed that statistical differences were observed between stage I and II, I and III A (P < 0.03), N0 and N1 (P < 0.021) in 3-year survival rate, between 2-3 and 4-6 cycle chemotherapy in 1-year survival rate (P < 0.007). CONCLUSION: Surgery combined with postoperative chemotherapy and radiotherapy is preferred for stages I and II, N0 and N1 lesions of SCLC.
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