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  • Title: U-turns and regulatory RNAs.
    Author: Franch T, Gerdes K.
    Journal: Curr Opin Microbiol; 2000 Apr; 3(2):159-64. PubMed ID: 10744992.
    Abstract:
    Conventional antisense RNAs, such as those controlling plasmid replication and maintenance, inhibit the function of their target RNAs rapidly and efficiently. Novel findings show that a common U-turn loop structure mediates fast RNA pairing in the majority of these RNA controlled systems. Usually, an antisense RNA regulates a single, cognate target RNA only. Recent reports, however, show that antisense RNAs can act as promiscuous regulators that control multiple genes in concert to integrate complex physiological responses in Escherichia coli.
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