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  • Title: Erythromycin resistance in Streptococcus pyogenes in Italy.
    Author: Bassetti M, Manno G, Collidà A, Ferrando A, Gatti G, Ugolotti E, Cruciani M, Bassetti D.
    Journal: Emerg Infect Dis; 2000; 6(2):180-3. PubMed ID: 10756153.
    Abstract:
    In a prospective study of acute pharyngitis in Italian children, 69 (38.3%) of 180 isolates of Streptococcus pyogenes were resistant to macrolides. S. pyogenes was eradicated in 12 (63.1%) of 19 patients with erythromycin-resistant S. pyogenes treated with clarithromycin and in 22 (88%) of 25 patients with erythromycin-susceptible strains. The constitutive-resistant phenotype was correlated with failure of macrolide treatment.
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