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  • Title: Hormonal reproductive status of women at menopausal transition compared to that observed in a group of midreproductive-aged women.
    Author: Sengos C, Iatrakis G, Andreakos C, Xygakis A, Papapetrou P.
    Journal: Clin Exp Obstet Gynecol; 2000; 27(1):54-6. PubMed ID: 10758802.
    Abstract:
    OBJECTIVE: To compare the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E2), testosterone (T) and dehydroepiandrosterone sulfate (DHEA-S) in perimenopausal women to the levels of the same reproductive hormones in younger women. METHODS: This was a case control study which compared the hormonal status (circulating levels of FSH, LH, PRL, T, E2, DHEA-S) between women at menopausal transition and younger mid-reproductive-aged controls. The t-test for independent samples was used. RESULTS: FSH, LH and E2 were higher, and T and DHEA-S were lower in perimenopausal women. CONCLUSION: The reproductive hormonal patterns in perimenopausal women favor a relatively hypergonadotropic hyper-estrogenic milieu.
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