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  • Title: Cloning and expression profile of chicken radixin.
    Author: Li W, Crouch DH.
    Journal: Biochim Biophys Acta; 2000 Apr 25; 1491(1-3):327-32. PubMed ID: 10760599.
    Abstract:
    Radixin is a member of the ERM (ezrin/radixin/moesin) family of cytoskeletal linkers. We have cloned chicken radixin as a 4.3 kb cDNA, which encodes an 80 kDa protein that is more than 98% identical to radixin from evolutionarily diverse species. High sequence homology (70-80%) also extends into the 3'-untranslated region (UTR) of the radixin gene. The 3'-UTR of moesin, but not ezrin, was also conserved, suggesting an essential, and possibly specific, regulatory function. A distinct pattern of radixin expression is seen in chicken tissues, suggesting a cell-type-specific function.
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