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  • Title: Mitral valve replacement in a patient with idiopathic thrombocytopenic purpura.
    Author: Oba J, Aoki H, Yoshida T, Kanaoka T, Oe K.
    Journal: Jpn J Thorac Cardiovasc Surg; 2000 Feb; 48(2):129-31. PubMed ID: 10769997.
    Abstract:
    Reports of a cardiac operation in a patient with idiopathic thrombocytopenic purpura are scarce. Here we present a case of successful mitral valve replacement in a patient with idiopathic thrombocytopenic purpura. Preoperative treatment with high-dosage gamma-globulin successfully increased the platelet count from 50,000/microliter to 80,000/microliter. Twenty units of platelet-rich plasma were administered during and after the operation. No other blood products were used. The postoperative convalescence was uneventful. Perioperative management for patients with idiopathic thrombocytopenic purpura undergoing open-heart surgery is discussed.
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