These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis of S-adenosyl-L-homocysteine hydrolase inhibitors and their biological activities.
    Author: Kitade Y, Kozaki A, Gotoh T, Miwa T, Nakanishi M, Yatome C.
    Journal: Nucleic Acids Symp Ser; 1999; (42):25-6. PubMed ID: 10780361.
    Abstract:
    Several nucleosides have been prepared as a possible inhibitor of human S-adenosyl-L-homocysteine (SAH) hydrolase for the development of anti-viral agents. Recently, SAH hydrolase has been considered as an attractive target for parasite chemotherapy for malaria. We report synthesis of several nucleosides including carbocyclic nucleosides and their inhibitory activities against recombinant malaria and human SAH hydrolases.
    [Abstract] [Full Text] [Related] [New Search]