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  • Title: Infective endocarditis complicated with progressive heart failure due to beta-lactamase-producing Cardiobacterium hominis.
    Author: Lu PL, Hsueh PR, Hung CC, Teng LJ, Jang TN, Luh KT.
    Journal: J Clin Microbiol; 2000 May; 38(5):2015-7. PubMed ID: 10790145.
    Abstract:
    We describe a 66-year-old woman with infective endocarditis due to Cardiobacterium hominis whose condition, complicated by severe aortic regurgitation and congestive heart failure, necessitated aortic valve replacement despite treatment with ceftriaxone followed by ciprofloxacin. The blood isolate of C. hominis produced beta-lactamase and exhibited high-level resistance to penicillin (MIC, >==256 microgram/ml) and reduced susceptibility to vancomycin (MIC, 8 microgram/ml).
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