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  • Title: Cytochalasin A inhibits the binding of phenylalanine ammonia-lyase mRNA to ribosomes during induction of phytoalexin in pea seedlings.
    Author: Sugimoto M, Toyoda K, Ichinose Y, Yamada T, Shiraishi T.
    Journal: Plant Cell Physiol; 2000 Feb; 41(2):234-8. PubMed ID: 10795320.
    Abstract:
    Cytochalasin A (CA) blocked the accumulation of phytoalexin and phenylalanine ammonia-lyase (PAL)-protein in pea tissues treated with a fungal elicitor but scarcely affected the PAL-mRNA content. Further analysis showed that CA decreased the PAL-mRNA bound to ribosomes. These results indicate that actin filaments are tightly associated with the translational process of the PAL gene.
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