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  • Title: [Demonstration of a major preexcitation syndrome during treatment of auricular flutter using intravenous injection of verapamil].
    Author: Chaudron JM, Lebacq E.
    Journal: Acta Cardiol; 1975; 30(2):137-50. PubMed ID: 1079999.
    Abstract:
    Electrophysiologic properties of various conduction pathways responsible for preexcitation syndrome are illdefined; they explain the incidence of arrhythmias : supraventricular tachycardia, atrial fibrillation and, in much rarer cases, flutter. The site of Verapamil activity is chiefly the atrioventricular junction, while its action on the refractory period of atrio-ventricular bypass is small and unforeseable. In a patient with type B. W.P.W. syndrome, complicated with atrial flutter Verapamil induced a preferential stimulation through the anomalous pathway. Right BBB which was obvious during the attack of atrial flutter, was hidden by the type B W.P.W. syndrome, the right branch being shunted by the anomalous pathway. The infrequency of atrial flutter in type B W.P.W. syndrome is emphasized.
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