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  • Title: Are the biologic and clinical effects of the COX-2-specific inhibitors an advance compared with the effects of traditional NSAIDs?
    Author: Simon LS.
    Journal: Curr Opin Rheumatol; 2000 May; 12(3):163-70. PubMed ID: 10803743.
    Abstract:
    This has been an unusual year for the accumulation of evidence regarding the clinical effects of inhibition of cyclooxygenase (COX)-1 and COX-2. This article reviews the available data regarding the clinical effects of the new COX-2-specific inhibitors, and speculates about the importance of the data as they relate to the treatment of patients with chronic pain and/or inflammation.
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