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  • Title: Quantal release parameters during fade of endplate potentials.
    Author: Branisteanu DD, Miyamoto MD, Volle RL.
    Journal: Naunyn Schmiedebergs Arch Pharmacol; 1975; 288(2-3):323-7. PubMed ID: 1080551.
    Abstract:
    An analog of hemicholinium-3 caused the fade of endplate potentials during repetitive stimulation at low rates. The quantal parameters of release were estimated during steady-state conditions before and in the presence of the drug. The fade of EPP's was associated with a decrease in quantal content (m). The decrease in m was, in turn, associated with a decrease in the binomial parameter n and an increase in the binomial parameter p. The changes in n and p are discussed in relation to available stores of transmitter and the probability of transmitter release.
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