These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Serum concentration of insulin-like growth factor-I in cord blood].
    Author: Wan G, Yu S, Liu J.
    Journal: Zhonghua Fu Chan Ke Za Zhi; 1998 Dec; 33(12):720-1. PubMed ID: 10806658.
    Abstract:
    OBJECTIVE: To evaluate the role of insulin-like growth factor-I (IGF-I) in fetal growth and placental growth. METHODS: Cord blood IGF-I was determined by radioimmunoassay (RIA) after serum samples were extracted with acid-ethanol. Linear correlation between variables was tested by calculating pearson's correlation coefficient. student's test was used to compare mean values between groups. RESULTS: In 102 tested samples, the concentration of cord blood serum IGF-I was correlated with the gestational age, the birth weight of neonates and placental weight (r = 0.32, P < 0.001, r = 0.68, P < 0.001, r = 0.75, P < 0.001). The mean serum level of IGF-I in the small-for-gestational-age (SGA) neonates was significantly lower than that in average-for gestational-age (AGA) (t = 4.77, P < 0.001), But the serum concentration of IGF-I in the Large-for-gestational-aga (LGA) neonates was significantly higher than that of AGA neonates (t = 7.97, P < 0.001). CONCLUSION: Those results suggested that IGF-I is an important regulator for fetal and placental growth and development. It has the key role for macrosomia and IUGR forming.
    [Abstract] [Full Text] [Related] [New Search]