These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A population-based case-control teratologic study of furazidine, a nitrofuran-derivative treatment during pregnancy.
    Author: Czeizel AE, Rockenbauer M, Sørensen HT, Olsen J.
    Journal: Clin Nephrol; 2000 Apr; 53(4):257-63. PubMed ID: 10809412.
    Abstract:
    OBJECTIVE: To study human teratogenic potential of furazidine treatment during pregnancy. DESIGN: Pair analysis of cases with congenital abnormalities and matched population controls. SETTING: The Hungarian Case-Control Surveillance of Congenital Abnormalities. PARTICIPANTS: 38,151 pregnant women who had newborn infants without any defects (population control group) and 22,865 pregnant women who had newborns or fetuses with congenital abnormalities between 1980 and 1996. RESULTS: In the case group, 157 (0.7%) and in the control group, 254 (0.7%) pregnant women were treated with furazidine. The case-control pair analysis did not indicate a teratogenic potential of furazidine use during the second to third months of gestation, i.e. in the critical period for major congenital abnormalities. CONCLUSION: Treatment with furazidine during pregnancy did not show teratogenic risk to the fetus.
    [Abstract] [Full Text] [Related] [New Search]