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  • Title: Thymus: central role in the immune system of the frog.
    Author: Volpe EP, Turpen JB.
    Journal: Science; 1975 Dec 12; 190(4219):1101-3. PubMed ID: 1081275.
    Abstract:
    In the leopard frog (Rana pipiens), the thymus profoundly influences immunologic development by providing virtually all the progenitor lymphocytic cells for the bone marrow and other peripheral lymphoid organs. The thymus houses a self-perpetuating population of lymphopoietic cells that originally self-differentiated in that gland.
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