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  • Title: Total synthesis of (-)-reveromycin B.
    Author: Cuzzupe AN, Hutton CA, Lilly MJ, Mann RK, Rizzacasa MA, Zammit SC.
    Journal: Org Lett; 2000 Jan 27; 2(2):191-4. PubMed ID: 10814279.
    Abstract:
    [structure: see text] The total synthesis of the epidermal growth factor inhibitor reveromycin B (2) is described. A novel, convergent, and stereoselective reaction sequence was utilized to construct the 5,6-spiroketal system 10 which was converted into the natural product 2 by a 16-step sequence.
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