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Title: Interaction of group A streptococci with human plasmin(ogen) under physiological conditions. Author: D'Costa SS, Boyle MD. Journal: Methods; 2000 Jun; 21(2):165-77. PubMed ID: 10816378. Abstract: A series of methods for analyzing the interaction of group A streptococci with the human plasminogen system are described. Examples of group A streptococcal isolates capable of assembling surface plasminogen activator activity when grown in human plasma are presented and the key requirements for this process are evaluated. The stabilities of cell-associated plasmin and plasminogen activator complexes are compared and a model for the interaction of group A streptococci with the plasminogen system in an infected host is presented.[Abstract] [Full Text] [Related] [New Search]