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  • Title: [T- and B-lymphocytes in the so-called collagenoses].
    Author: Standhofer M, Fritz J, Grond K, Klein G.
    Journal: Z Rheumatol; 1975; 34(11-12):418-24. PubMed ID: 1082214.
    Abstract:
    Lymphocytes of peripheral blood of patients with systemic lupus erythematosus, scleroderma and dermatomyositis were investigated, and relatively, with regard to T- or B-cell characteristics. T-lymphocytes of most patients with SLE were decreased both absolutely. B-lymphocytes mostly showed only a relative increase. Successful immunosuppressive treatment usually accompanied by normalization of T-cell number and with decrease of B-cells. This differentiation of lymphocytes is an additional aid in the determination of activity of SLE and a useful index of immunosuppressive-cytostatic treatment.
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