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  • Title: An anterograde degeneration study of the distribution of regenerating rat myelinated fibers in the silicone chamber model.
    Author: Alzate LH, Sutachan JJ, Hurtado H.
    Journal: Neurosci Lett; 2000 May 26; 286(1):17-20. PubMed ID: 10822142.
    Abstract:
    Specificity of reinnervation after a peripheral nerve lesion has given rise to considerable controversy. As a contribution to solving this issue we have evaluated the specificity of reinnervation of the peroneal nerve after a complete transection of the sciatic nerve repaired with an 8 mm silicone tube, leaving a 4 mm gap between the nerve stumps. Our findings reveal unspecificity of reinnervation of the distal peroneal branch. This lack of specificity is shown by a random distribution of fibers originating from both proximal branches at the level of the tube and at distal peroneal and tibial branches, argue against specificity of regeneration in this model.
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