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  • Title: Different surface glycoprotein patterns on human T-, B- and leukemic-lymphocytes.
    Author: Andersson LC, Wasastjerna C, Gahmberg CG.
    Journal: Int J Cancer; 1976 Jan 15; 17(1):40-6. PubMed ID: 1082448.
    Abstract:
    We have labelled the exposed surface glycoproteins of human blood T- and B-lymphocytes and cells from patients with chronic lymphocytic leukemia by the galactose oxidase-tritiated sodium borohydride method. The labelled glycoproteins were separated by polyacrylamide slab gel electrophoresis and visualized by autoradiography. The T- and B-lymphocytes show different and characteristic surface glycoprotein patterns. The surface glycoprotein patterns of the leukemic cells differ from those of normal, non-malignant lymphocytes. A relationship between the altered surface glycoprotein pattern of leukemic cells and the expression of leukemia-associated antigens is discussed.
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