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  • Title: Biosynthesis of isoprenoids in Escherichia coli: stereochemistry of the reaction catalyzed by farnesyl diphosphate synthase.
    Author: Leyes AE, Baker JA, Poulter CD.
    Journal: Org Lett; 1999 Oct 07; 1(7):1071-3. PubMed ID: 10825960.
    Abstract:
    [formula: see text] Farnesyl diphosphate (FPP) synthase from Escherichia coli catalyzes the condensation of isopentenyl diphosphate (IPP) and geranyl diphosphate (GPP) with selective removal of the pro-R hydrogen at C2 of IPP, the same stereochemistry observed for the pig liver, yeast, and avian enzymes.
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