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  • Title: [Effect of thymocyte autotransplantation on postradiation regeneration of hematopoiesis].
    Author: Fedotova MI, Zimin IuI.
    Journal: Biull Eksp Biol Med; 1975 Jun; 79(6):32-4. PubMed ID: 1083259.
    Abstract:
    Experiments were conducted on Wistar rats irradiated in a dose of 400 R; a study was made of the effect of thymocyte autotransplantation (4-10(8)--8-10(8)) on the restoration of cell number of the bone marrow and the spleen. There was revealed a significant stimulating effect of autotransplantation of thymocytes on the erythroid and granulocytic series in the bone marrow and on the lymphoid one in the spleen during the restoration (the 5 th-- 7 th days) after the irradiation. Irradiation of the thymocyte suspension with gamma-rays in a dose of 10 000 R failed to prevent the effect of autotransplantation on the bone marrow, but decreased its stimulating effect. A conclusion was drawn on the interaction of the administered thymocytes with the stem hemopoietic cell.
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