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  • Title: The r.b.e. of different energy neutrons as measured by the heamatopoietic spleen-colony technique.
    Author: Carsten AL, Bond VP, Thompson K.
    Journal: Int J Radiat Biol Relat Stud Phys Chem Med; 1976 Jan; 29(1):65-70. PubMed ID: 1083841.
    Abstract:
    The spleen-colony technique has been used for determining the relative biological effectiveness (r.b.e.) for several energies of neutron radiation. Donor mice were exposed for fission and accelerator-generated neutrons at a variety of doses and energies. Immediately after exposure, donor bone-marrow was removed from the hind legs, and standard amounts were injected intravenously into lethally X-irradiated recipients. After 7 days the recipients spleens were evaluated for surface colonies. Dose-response curves were obtained for each type of radiation and the Do was determined. The neutron r.b.e. values from the Do compared with 250kVp X-rays were: reactor 1.58, 252Cf 1:59, and accelerator varied from 2.85 at 1.0 Mev to 0.85 at 13.4 MeV.
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