These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The potential for vaccine development against chlamydial infection and disease.
    Author: Brunham RC, Zhang DJ, Yang X, McClarty GM.
    Journal: J Infect Dis; 2000 Jun; 181 Suppl 3():S538-43. PubMed ID: 10839755.
    Abstract:
    Chlamydia trachomatis and Chlamydia pneumoniae appear to share a common immunobiology with about 80% of their protein coding genes being orthologs. Progress in DNA vaccine development for C. trachomatis suggests that such a subunit approach may prove useful for C. pneumoniae. The recent finding that it is possible to select for chlamydiae with targeted mutations in key metabolic genes together with the new knowledge of the chlamydia genome also suggests that it may be possible to develop live attenuated strains of chlamydiae for use as vaccine.
    [Abstract] [Full Text] [Related] [New Search]