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  • Title: [Early functional disorders in 3 children exhibiting an obstructive syndrome and an alpha 1 antitrypsin deficiency].
    Author: Gaultier C, Mensch B, Grimfeld A, Girard F, Gerbeaux J.
    Journal: Poumon Coeur; 1975; 31(5):291-5. PubMed ID: 1083978.
    Abstract:
    The respiratory function is studied in 3 children, two of which 4 years in age, exhibiting a respiratory obstructive syndrome and an alpha1-antitrypsin deficiency. The study of the respiratory function is global and regional. The disorders noted include a ventilatory asynchronism, a distension, regional anomalies of ventilation and perfusion. The ventilatory asynchronism appears to be an early disorder in the course of alpha1-antitrypsin deficiency. These results have to be related with the development of the elastic fibers during the child's growth.
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