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  • Title: [Distribution of chromosome breakage point induced by arabinosylcytosine on in-vitro human lymphocytes].
    Author: Ayraud N, Cantrelle C, Lloyd M.
    Journal: Ann Genet; 1976 Mar; 19(1):29-35. PubMed ID: 1084119.
    Abstract:
    The cytogenetic effects of arabinosyl cytosine on human leukocytes in vitro has been studied using continuous and discontinuous treatments. Optimum activity occurs at the end of the S period. Interchromosomal distribution of breaks is non-random. The hypothesis of a very late replication for some chromatid segments is discussed. The relations between banding and the position of breaks are discussed.
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