These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [T-lymphocyte subpopulation in the blood of patients with chronic lymphocytic leukemia].
    Author: Holowiecki J, Stella B, Krawczyk M, Rudzka E.
    Journal: Acta Haematol Pol; 1976; 7(2):111-6. PubMed ID: 1084671.
    Abstract:
    In 40 healthy subjects and 80 patients with chronic lymphocytic leukaemia (CLL) rosette formation test with sheep erythrocytes subjected to the action of neuraminidase (nRTB), immunofluorescent investigation of membrane immunoglobulins (BIg) and a combined test (nRTB + BIg) were performed. The relative number of rosette-forming cells (T lymphocytes) was much lower in the group of CLL patients (0.16 +/- 0.08 1/1) than in controls (0.64 +/- 0.12 1/1). The absolute number of T lymphocytes (BLLT) was, however, significantly higher in patients with CLL 5.1 +/- 4.4 G/L) than in controls (0.98 +/- 0.28 G/L). The relative number of bireceptor cells was 0.0045 +/- 0.0093 1/1 in CLL patients and that of null-cells 0.24 +/- 0.17 1/1. Analogous values in the control group were 0.0089 +/- 0.009 1/1 and 0.21 +/- 0.091 1/1. The possible causes of this rise in the absolute number of T lymphocytes in CLL may by: 1) proliferation of both subpopulations of lymphocytes, 2) reaction of T lymphocytes against leukaemic cells, 3) disturbances of equilibrium between B and T lymphocytes.
    [Abstract] [Full Text] [Related] [New Search]