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  • Title: [Treatment of maternal hyperthyroidism and fetal goiter].
    Author: Bellini P, Marinetti E, Arreghini A, Andreotti C, Kirm V, Roncaglia N.
    Journal: Minerva Ginecol; 2000; 52(1-2):25-7. PubMed ID: 10851860.
    Abstract:
    A fetal goitre is a potentially dangerous phenomenon because of mechanical obstruction and possible fetal thyroid function disorders. During pregnancy women with a history of Graves' disease under treatment with propylthiouracil (PTU) have an increased risk for fetal goitre. In this report a patient with Graves' disease diagnosed in early pregnancy and treated with PTU which resulted in a fetal goitre is described. The fetal thyroid status, investigated by percutaneous fetal umbilical cord blood sampling, was normal and the reduction of PTU dosage was sufficient to decrease goitre volume.
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