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  • Title: Structural hair shaft abnormalities in hypomelanosis of ito and other ectodermal dysplasias.
    Author: Selvaag E, Aas AM, Heide S.
    Journal: Acta Paediatr; 2000 May; 89(5):610-2. PubMed ID: 10852202.
    Abstract:
    Hair samples from patients with different ectodermal dysplasias; hypohidrotic ectodermal dysplasia, pachyonychia congenita, tricho-dento-osseous syndrome, tricho-rhino-phalangeal syndrome, and hypomelanosis of Ito were investigated using a scanning electron microscope. The hairs of the patients showed different structural abnormalities; twisted hairs, longitudinal grooves, trichorrhexis nodosa as well as variations in the hair caliber. Hair shaft abnormalities, as in our patients with tricho-dento-osseous syndrome, and hypomelanosis of Ito have so far not been described.
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