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  • Title: Primary cutaneous B cell lymphoma during methotrexate therapy for rheumatoid arthritis.
    Author: Fam AG, Perez-Ordonez B, Imrie K.
    Journal: J Rheumatol; 2000 Jun; 27(6):1546-9. PubMed ID: 10852288.
    Abstract:
    A patient with rheumatoid arthritis developed a reversible, primary cutaneous, large B cell lymphoma during prolonged methotrexate (MTX) treatment. Regression of the skin lesions after discontinuation of the drug suggested a close relationship to MTX. Increased clinical awareness, discontinuation of MTX, and close observation are important in the initial management of this rare lymphoproliferative disorder.
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