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  • Title: Three-dimensional quantitative structure-activity relationship analyses of RGD mimetics as fibrinogen receptor antagonists.
    Author: Miyashita M, Akamatsu M, Hayashi Y, Ueno T.
    Journal: Bioorg Med Chem Lett; 2000 May 01; 10(9):859-63. PubMed ID: 10853647.
    Abstract:
    In order to better understand the structural requirements of fibrinogen receptor antagonists, variations in the platelet aggregation inhibitory activity of a series of RGD mimetics were examined using techniques for the analysis of three-dimensional quantitative structure activity relationship, such as CoMFA.
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