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  • Title: Neonatal pyridoxine responsive convulsions due to isoniazid therapy.
    Author: McKenzie SA, Macnab AJ, Katz G.
    Journal: Arch Dis Child; 1976 Jul; 51(7):567-8. PubMed ID: 1085609.
    Abstract:
    A 17-day-old infant on isoniazid therapy 13 mg/kg daily from birth because of maternal tuberculosis was admitted after 4 days of clonic fits. No underlying infective or biochemical cause could be found. The fits ceased within 4 hours of administering intramuscular pyridoxine, suggesting an aetiology of pyridoxine deficiency secondary to isoniazid medication.
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