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  • Title: Warning! One buflomedil may hide another one!
    Author: Chiffoleau A, Yatim D, Garrec F, Veyrac G, Raoult P, Larousse C, Bourin M.
    Journal: Therapie; 2000; 55(1):221-3. PubMed ID: 10860027.
    Abstract:
    A 75-year-old woman experienced fever and convulsions. She was treated for diabetes mellitus, angina pectoris and also for arteritis with Buflomedil Merck (3 tab/d). Further investigations failed to find any aetiology. Buflomedil dosage was elevated to 6.3 mg/l (N = 4-4.5 mg/l). The drug was discontinued and there was no recurrence of symptoms. There was no evidence of error in dosage or interaction. A failure of the generic product was suspected. Only a pharmacist solved the problem. Fonzylane (buflomedil) had recently been switched to Buflomedil Merck. The patient misunderstood the change and took both drugs! Our purpose is not to report a known effect but to emphasize the importance of extending the information given to the patient and the risk of misuse of the generic product.
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