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  • Title: Fluorescein angiography and vitamin A and oxalate levels in fundus albipunctatus.
    Author: Carr RE, Margolis S, Siegel IM.
    Journal: Am J Ophthalmol; 1976 Oct; 82(4):549-58. PubMed ID: 1086061.
    Abstract:
    Two patients had fundus albipunctatus, one of the variants of congenital stationary night blindness. Neither the white dots in the retinas of these patients nor the retarded course of dark adaptation characteristically associated with the disease could be attributed to vitamin A deficiency or raised oxalate levels since both substances were present in normal amounts. Fluorescin angiography showed multiple discrete lesions in the pigment epithelium not coincident with the ophthalmoscopically visible changes. Since the pigment epithelium is the storage site for bleached visual pigment, these findings suggest abnormalities that underlie the major functional deficit in this disease, that is, the slow recovery of retinal sensitivity.
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