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  • Title: Ontogeny of the antibody-forming cell line in mice. I. Kinetics of appearance of mature B cells.
    Author: Rosenberg YJ, Cunningham AJ.
    Journal: Eur J Immunol; 1976 Jul; 5(7):444-7. PubMed ID: 1086243.
    Abstract:
    The development of functionally mature B cells in the liver and spleen of fetal and neonatal CBA mice has been followed. A mature B cell is defined as one giving rise to antibody-producing progeny within 2 days in culture. Very few such B cells are found during fetal life. After birth there is a rapid rise in the numbers reaching 1/3 of adult levels in the 7-day-old spleen.
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