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  • Title: Spinal atypical teratoid/rhabdoid tumor in an infant.
    Author: Tamiya T, Nakashima H, Ono Y, Kawada S, Hamazaki S, Furuta T, Matsumoto K, Ohmoto T.
    Journal: Pediatr Neurosurg; 2000 Mar; 32(3):145-9. PubMed ID: 10867562.
    Abstract:
    Atypical teratoid/rhabdoid tumor of the central nervous system in infancy and childhood was established as an entity based on histological, immunohistochemical, and cytogenetic studies. We report the case of a 7-month-old girl who presented with progressive paraplegia and hypesthesia of her legs. Imaging studies revealed a spinal cord mass occupying the entire spinal canal below the T(7) level. Through a T(12)-L(3) laminectomy, the intramedullary tumor was partially debulked. Histologically, the tumor specimen had rhabdoid cells, and immunostaining showed vimentin and cytokeratin positivity. No abnormality of chromosome 22q was detected with the fluorescence in situ hybridization method.
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