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  • Title: The role of preoperative chemotherapy in the treatment of infantile fibrosarcoma.
    Author: Kurkchubasche AG, Halvorson EG, Forman EN, Terek RM, Ferguson WS.
    Journal: J Pediatr Surg; 2000 Jun; 35(6):880-3. PubMed ID: 10873030.
    Abstract:
    Infantile fibrosarcoma (IFS) is a rare tumor most often affecting the extremities of infants and young children. Unlike its adult counterpart, IFS has a low potential for metastatic spread, and surgical extirpation alone has therefore resulted in an excellent prognosis. The amputation rate, however, exceeds 50%. The dramatic response in 2 recent cases to preoperative chemotherapy, given in an attempt to avoid amputation, prompted this report and a review of the literature.
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