These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ontogeny of the antibody-forming cell line in mice. II. Maturation of B cells during fetal development.
    Author: Rosenberg YJ, Cunningham AJ.
    Journal: J Immunol; 1976 Nov; 117(5 Pt 1):1618-21. PubMed ID: 1087319.
    Abstract:
    This paper maps the developmental stage reached by B cells in mouse fetuses of different ages. The "maturity" of these cells was assessed in a functional way by measuring the time taken for cells to generate antibody-forming progeny when injected into carrier-primed irradiated adult hosts and challenged daily with antigen. A steady uninterrupted progression in development of B cells occurred between 13 days of gestation and birth. There was no evidence for a stage during which B cells could only be paralyzed and not induced by antigen.
    [Abstract] [Full Text] [Related] [New Search]