These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Transcriptional control: imprinting insulation.
    Author: Wolffe AP.
    Journal: Curr Biol; 2000 Jun 15; 10(12):R463-5. PubMed ID: 10873799.
    Abstract:
    Recent studies on the transcriptional regulation of two linked, imprinted genes, Igf2 and H19, have provided evidence for a novel mechanism of epigenetic control. DNA methylation controls the activity of an insulator element located between the two linked genes by regulating the binding of the zinc-finger protein CTCF.
    [Abstract] [Full Text] [Related] [New Search]